The Impact of a Caffeinated Sports Drink on Performance

Completed · Not applicable · Has a placebo group

Conditions studied: Dehydration, Dehydration Related to Exercise

In brief

Caffeine is known to enhance physical and mental performance, but few beverages combine caffeine with electrolytes and carbohydrates to enhance exercise performance. This study evaluates a caffeinated electrolyte-glucose drink's effect on endurance, strength, and cognition. Using a repeated-measures, cross-over design, 20 trained cyclists will complete one familiarization and four randomized 3-hour experimental trials (Liquid I.V.™ Energy Multiplier, Hydration Multiplier, Sugar-Free Hydration Multiplier, and water). Each trial includes 2 hours of cycling in a warm environment (32ºC), followed by strength and cognitive assessments. Cycling performance, capillary blood, urine, and expiratory gases will be collected.

Key facts

Study ID

NCT06721793

Run by

Arizona State University

People needed

26

Starts

2025-12-12

Expected to finish

2025-12-16

Last updated by the study team

2026-01-27

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age 18-55
• Healthy and injury-free (muscle, skeletal) for greater than 2 months
• Active cyclists who train at least 3 times per week
• Body mass index (BMI) range of 18.5-30 kg/m2

You may not qualify if…

• • History of caffeine sensitivity
• Cancer Diagnosis during the last 5 years
• Pregnancy
• History of renal disease, hypertension
• History of a heat stroke
• Use of testosterone therapy
• Adults who are unable to consent (impaired decision-making capacity)

Where it is running

• Arizona State University - Hydration Science Lab — Phoenix, Arizona, United States

Full record on ClinicalTrials.gov

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