MRgLITT for mTLE: A PROBE Trial

Recruiting now · Not applicable

Conditions studied: Temporal Lobe Epilepsy (TLE)

In brief

How does magnetic resonance-guided laser interstitial thermal therapy (MRgLITT) impact clinical prognosis in mesial temporal lobe epilepsy (mTLE)?

Key facts

Study ID

NCT06720922

Run by

Beijing Tiantan Hospital

People needed

120

Starts

2025-07-21

Expected to finish

2028-01-01

Last updated by the study team

2026-01-21

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 18-65 years.
• Drug-resistant mesial temporal lobe epilepsy.
• Seizure frequency ≥ 1 time /month.
• Participants approved.

You may not qualify if…

• History of brain surgery.
• Intracranial space occupying lesions.
• Individuals with significant medical comorbidities or conditions that pose an excessive risk for surgery, such as severe cardiovascular disease, respiratory disorders, or uncontrolled systemic infections.

Where it is running

• Beijing Tiantan Hospital — Beijing, Beijing Municipality, China (enrolling)

Full record on ClinicalTrials.gov

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