Idiopathic Central Precocious Puberty and Associated Neurodevelopmental Syndromes and Pathologies: Evaluation of Frequency and Comparison of Diagnostic and Developmental Characteristics
Recruiting now
Conditions studied: Central Precocious Puberty (CPP)
In brief
Observational, retrosopective, single-centre, non-profit study focused on the frequency of Central Precocious Puberty idiopathic, or associated to Neurodevelopmental Syndromes and Pathologies, and comparison of diagnostic and developmental characteristics of patients.
Key facts
- Study ID
- NCT06720844
- Run by
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
- People needed
- 300
- Starts
- 2024-03-13
- Expected to finish
- 2027-05-13
- Last updated by the study team
- 2026-03-12
Who can join
Age: any, up to 18. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients diagnosed with Central Precocious Puberty presenting an indication to undertake treatment with GnRH analogue: Appearance of secondary sexual characteristics (thelarche or gonadarche) before the age of 8 for females and 9 for males; Acceleration of the rate of statural growth and advancement of bone age one year older than the chronological age; LH peak > 5 IU/L on GnRH test and a longitudinal uterine diameter > 36 mm in females, with or without the appearance of endometrial rhyme;
- Age at onset of entral Precocious Puberty between 2 and 8 years (females) or between 2 and 9 years (males);
- Age at enrollment < 18 years;
- Follow-up of at least 12 months;
- Obtaining informed consent from parents/legal guardian of peduatric patients.
You may not qualify if…
- Isolated telarche and/or pubarche;
- Peripheral forms of precocious puberty;
- Patients diagnosed with primary organic Central Precocious Puberty due to tumour- or non-tumour-causing hypothalamic lesions.
Where it is running
- IRCCS Azienda Ospedaliero-Universitaria di Bologna — Bologna, Bolgona, Italy (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.