A Real-world Study on the Treatment of Non-small Cell Lung Cancer With Leptomeningeal Metastasis in China

Recruiting now

Conditions studied: Meningeal Metastasis, Non-Small Cell Lung Cancer

In brief

This is a retrospective and prospective study planned to include NSCLC patients with Leptomeningeal metastasis (LM) and treated with antitumor therapy after 2018, from multiple centers such as the First Affiliated Hospital of Guangzhou Medical University, Guangdong Sanjiu Brain Hospital, etc., aiming to establish a database related to the treatment strategies of LM patients, and to evaluate the efficacy (eg. Overall Survival/Time to Failure) and safety of different treatment strategies of LM patients, etc., as well as the significance of concomitant testing in LM patients.

Key facts

Study ID

NCT06718972

Run by

Guangzhou Medical University

People needed

1000

Starts

2024-09-01

Expected to finish

2028-12-31

Last updated by the study team

2025-04-27

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• non-small cell lung cancer patients with Leptomeningeal metastases diagnosed after January 2018;
• Patients who underwent antitumor therapy after diagnosis of LM.

You may not qualify if…

• Patients with small cell lung cancer components;
• complicated with tumors other than non-small cell lung cancer.

Where it is running

• Guangdong Sanjiu Brain Hospital — Guangzhou, Guangdong, China (enrolling)
• the First Affiliated Hospital of Guangzhou Medical University — Guangzhou, Guangdong, China (enrolling)

Full record on ClinicalTrials.gov

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