Effect of Limb Occlusion Pressure Attainment on Cardiovascular, Perceptual, and Performance Responses

Completed · Not applicable

Conditions studied: Blood Flow Restriction (BFR) Training Effects, Arterial Stiffness, Blood Pressure, Muscle Morphology, Perceptions

In brief

To test the effect of limb occlusion pressure attainment in the supine, seated, and standing position on exercise performance, vascular physiology, and muscle.

Key facts

Study ID

NCT06718582

Run by

Teri Herberger

People needed

27

Starts

2025-02-01

Expected to finish

2025-04-15

Last updated by the study team

2025-10-10

Who can join

Age: 18 and older, up to 40. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Physically active (> 1,000 MET/min/wk) for at least six months. Weight stable for previous 6 months (+/-2.5 kg) Female subjects only- reported regular menstrual cycles for the last 2 years

You may not qualify if…

• BP>140/90 mmHg
• BMI>40 kg/m2
• Diabetes
• Familial hypercholesterolemia
• Past or current history of CHD, stroke or major CVD events. Respiratory diseases (not including asthma), endocrine or metabolic, neurological, or hematological disorders that would compromise the study or the health of the subject.
• Women must not be pregnant, plan to become pregnant during the study, or be nursing
• Active renal or liver disease
• All medications and supplements that influence dependent variables*
• Recent surgery < 2 months
• Alcohol abuse
• Sleep apnea
• Claustrophobia

Where it is running

• Salisbury University — Salisbury, Maryland, United States

Full record on ClinicalTrials.gov

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