A Study to Evaluate Safety, Tolerability and Efficacy of AP306 at Fixed Doses in Dialysis Participants With Hyperphosphatemia
Recruiting now · Phase 2 · Has a placebo group
Conditions studied: Hyperphosphatemia, Chronic Kidney Disease Requiring Chronic Dialysis, End Stage Renal Disease on Dialysis
In brief
This study is being conducted to characterize the safety, tolerability, and efficacy of AP306 at fixed doses in adults with hyperphosphatemia receiving maintenance hemodialysis.
Key facts
- Study ID
- NCT06712654
- Run by
- R1 Therapeutics
- People needed
- 168
- Starts
- 2026-06-01
- Expected to finish
- 2027-03-31
- Last updated by the study team
- 2026-08-03
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Sichuan Provincial People's Hospital — Chengdu, Sichuan, China (enrolling)
- California Institute of Renal Research — Chula Vista, California, United States (enrolling)
- Academic Medical Research Institute — Los Angeles, California, United States (enrolling)
- North America Research Institute — San Dimas, California, United States (enrolling)
- Colorado Kidney Care — Denver, Colorado, United States (enrolling)
- DaVita Clinical Research — Middlebury, Connecticut, United States (enrolling)
- PACT Kidney Care — Orange, Connecticut, United States (enrolling)
- US Renal Care - Fort Myers South — Fort Myers, Florida, United States (enrolling)
- Nephrology & Hypertension Specialists — Dalton, Georgia, United States (enrolling)
- St. Clair Nephrology Research — Shelby, Michigan, United States (enrolling)
- DaVita Clinical Research Edina — Edina, Minnesota, United States (enrolling)
- Johnson County Clinical Trials — Kansas City, Missouri, United States (enrolling)
- DaVita Clinical Research — Las Vegas, Nevada, United States (enrolling)
- R1 Therapeutics Clinical Trial Site — Albuquerque, New Mexico, United States (enrolling)
- NY Kidney & Hypertension Medicine — Ridgewood, New York, United States (enrolling)
- US Renal Care - Alexis — Toledo, Ohio, United States (enrolling)
- Sunbeam Research — Greenville, Texas, United States (enrolling)
- DaVita Clinical Research — Houston, Texas, United States (enrolling)
- Gamma Medical Research — McAllen, Texas, United States (enrolling)
- US Renal Care - South San Antonio — San Antonio, Texas, United States (enrolling)
- US Renal Care - Westover Hills — San Antonio, Texas, United States (enrolling)
- DaVita Clinical Research San Antonio — San Antonio, Texas, United States (enrolling)
- US Renal Care — Waxahachie, Texas, United States (enrolling)
- DaVita Clinical Research Norfolk — Norfolk, Virginia, United States (enrolling)
- Peking University First Hospital — Beijing, Beijing Municipality, China (enrolling)
Full record on ClinicalTrials.gov
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