MRI Analysis in the Growth of Cerebral Aneurysms

Recruiting now · Not applicable

Conditions studied: Unruptured Intracranial Aneurysm

In brief

An intracranial aneurysm is defined as a localized dilatation of the cerebral arteries, which can potentially lead to rupture and subsequent hemorrhagic stroke. The mechanisms by which aneurysms develop and grow remain unknown. The objective of this project is to utilize MRI, a routine non-invasive examination for detecting and following up aneurysms, to identify visually and quantitatively an aneurysm growth and relevant biomarkers that can predict the risk of aneurysm development.

Key facts

Study ID

NCT06705452

Run by

CHU de Reims

People needed

281

Starts

2026-07-08

Expected to finish

2032-07-08

Last updated by the study team

2026-08-07

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients with one or more unruptured intracranial aneurysms followed up at the participating center. Patients may have other ruptured and/or treated aneurysms
• Patient older than 18 years
• Patient consenting to participate to the study
• Patient enrolled in the national healthcare insurance program

You may not qualify if…

• Patients who have already received surgical or endovascular treatment for all their aneurysm(s), or who are due to receive such treatment in less than 2 months.
• Patients with only ruptured aneurysm(s)
• Patients with arteriovenous malformations (treated or untreated)
• Patients with a contraindication to MRI
• Patients with an allergy to one of the contrast agents (Iodixanol, Gadoteric acid)
• Pregnant or breast-feeding patients
• Patients protected by law.

Where it is running

• Damien JOLLY — Reims, France (enrolling)

Full record on ClinicalTrials.gov

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