Working Memory Training for People Aging With HIV
Completed · Early Phase 1
Conditions studied: Cognitive Change
In brief
The present study investigates the feasibility of working memory training in people aging with HIV (PAWHIV). In a cross-over design this stage 1 feasibility trial, will evaluate acceptability, and estimate possible effect sizes related to working memory training by examining potential differential effects in PAWHIV and those aging without HIV. This project highlights the importance of tailored cognitive assessments and interventions, engaging with underrepresented communities to enhance inclusivity in cognitive health research.
Key facts
- Study ID
- NCT06699927
- Run by
- Northeastern University
- People needed
- 100
- Starts
- 2024-07-15
- Expected to finish
- 2026-03-06
- Last updated by the study team
- 2026-04-20
Who can join
Age: 50 and older, up to 85. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- 50-85 years of age
- Able to understand and speak English and follow study procedures
- Does not have a psychological or neurological condition that would prevent being able to give consent to participate
- Not currently involved in any other cognitive or memory training studies
You may not qualify if…
- Formal diagnosis of dementia or other neurological disease, including Mild cognitive impairment.
- A final total score below 17 on Montreal Cognitive Assessment - Blind (telephone) version.
- Score of 10 or more on the Generalized Anxiety Questionnaire (GAD7; Spitzer et al., 2006, Archives of Internal Medicine), indicating presence of moderate or severe anxiety
- Score of 9 or more on Geriatric depression scale (GDS15; Yesavage et al., 1982) indicating presence of moderate or severe depression
- Abnormal visual acuity prohibitive of tablet-based training.
- Physical handicap (motor or perceptual) that would impede training procedures.
- Medical illness requiring treatment and/or significant absences during the study timeline.
- Current evidence or 2-yr history of seizures, focal brain lesion, or head injury with loss of consciousness.
- Current alcohol consumption exceeds 14 drinks per week.
- Self-reported illicit drug use.
Where it is running
- Northeastern University — Boston, Massachusetts, United States
Full record on ClinicalTrials.gov
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