A Study to Assess the Safety, Pharmacokinetics, and Tolerability of ABI-1179 in Healthy Subjects and in Subjects Seropositive for HSV-2 With Recurrent Genital Herpes
Completed · Phase 1 · Has a placebo group
Conditions studied: Recurrent Genital Herpes Simplex Type 2
In brief
This study is designed to assess safety, tolerability, and pharmacokinetics (PK) of single ascending dose (SAD) of ABI-1179 in Part A in healthy participants and multiple-ascending doses (MAD) of ABI-1179 in Part B in participants seropositive for Herpes Simplex Virus Type 2 (HSV-2) with recurrent genital herpes. Effect of food will also be evaluated in Part A.
Key facts
- Study ID
- NCT06698575
- Run by
- Assembly Biosciences
- People needed
- 103
- Starts
- 2024-12-08
- Expected to finish
- 2026-01-19
- Last updated by the study team
- 2026-03-23
Who can join
Age: 18 and older, up to 60. Sex: any. Healthy volunteers: accepted.
Where it is running
- Alliance for Multispecialty Research — Kansas City, Missouri, United States
- Rochester Clinical Research — Rochester, New York, United States
- Seattle Clinical Research Center — Seattle, Washington, United States
- University of Washington Virology Research Clinic — Seattle, Washington, United States
- East Sydney Doctors — Darlinghurst, Australia, Australia
- Royal Melbourne Hospital — Parkville, Australia, Australia
- Taylor Square Private Clinic — Surry Hills, Australia, Australia
- Momentum Clinical Research — Sydney, Australia, Australia
- Canopy Clinical Wollongong — Wollongong, Australia, Australia
- Momentum Sunshine — Melbourne, Au, Australia
- New Zealand Clinical Research — Auckland, New Zealand, New Zealand
- New Zealand Clinical Research — Christchurch, New Zealand, New Zealand
- Pacific Clinical Research Network — Nelson, New Zealand, New Zealand
- Momentum Palmerston North — Palmerston North, New Zealand, New Zealand
- Pacific Clinical Research Network — Rotorua, New Zealand, New Zealand
- Pacific Clinical Research Network — Upper Hutt, New Zealand, New Zealand
- Momentum Kapiti — Waikanae, New Zealand, New Zealand
- Pacific Clinical Research Network — Hamilton, New, New Zealand
Full record on ClinicalTrials.gov
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