Effectiveness of Anti-Inflammatory Drugs for Preventing Pain Versus Treating Pain During Medical Abortion From 13 to 22 Weeks at Hung Vuong Hospital
Recruiting now · Not applicable
Conditions studied: Pain Management, Anti-Inflammatory Agents, Non-Steroidal, Abortion, Spontaneous
In brief
The goal of this clinical trial is to assess the effectiveness of non-steroidal anti-inflammatory drugs (NSAIDs) for prophylactic pain relief compared to on-demand pain relief during medical abortion for pregnancies between 13 and 22 weeks at Hung Vuong Hospital in Ho Chi Minh City. The main questions it aims to answer are: 1. Does prophylactic use of NSAIDs reduce pain compared to on-demand use during medical abortion? 2. What are the potential adverse effects of NSAIDs in this context? Researchers will compare a group receiving prophylactic NSAIDs to a control group receiving on-demand pain relief to determine if the prophylactic approach leads to improved pain management outcomes. Participants will: * Be given NSAIDs either as a preventative measure or upon the onset of pain. * Be monitored for pain levels using validated pain scales, any side effects, and outcomes of the abortion procedure.
Key facts
- Study ID
- NCT06696573
- Run by
- Le Thi Kieu Trang
- People needed
- 180
- Starts
- 2024-12-13
- Expected to finish
- 2025-12-01
- Last updated by the study team
- 2025-03-13
Who can join
Age: 18 and older. Sex: female. Healthy volunteers: accepted.
You may qualify if…
- Pregnant women aged 18 years or older.
- No mental illness.
- Gestational age between 13 and 22 weeks (based on the last menstrual period with a regular menstrual cycle and accurate recall of the last menstrual period, or based on a first-trimester ultrasound) with an indication of stillbirth, fetal malformation requiring termination, or voluntary abortion with counseling and understanding of the abortion procedure.
- Willing to participate in the study.
- Capable of reading and signing the informed consent form.
- Able to provide personal information independently.
You may not qualify if…
- Medical conditions contraindicating medical abortion: bleeding disorders, anticoagulant use, moderate to severe anemia.
- Cardiovascular conditions: heart failure, mitral valve stenosis, embolism, uncontrolled hypertension.
- Other medical conditions: renal failure, adrenal gland disorders, severe asthma, liver and biliary diseases, glaucoma.
- Active pelvic inflammatory disease or acute genital infections.
- Previous uterine surgery.
- Placenta previa or central placenta previa.
- Uterine malformations.
- History of allergy to NSAIDs, Mifepristone, or Misoprostol.
- Unwillingness to participate in the study.
Where it is running
- Hung Vuong Hospital — Ho Chi Minh City, Vietnam (enrolling)
Full record on ClinicalTrials.gov
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