Jockey Club Precision Prevention Programme on Young Onset Diabetes

Recruiting now · Not applicable

Conditions studied: Diabetes, Pre Diabetes, Hypertension, Dyslipidemia, Obesity

In brief

This is a community-based implementation program consisting of multiple components delivered by a multidisciplinary team to detect and prevent young onset diabetes with precision and value using biogenetic markers, digital tools, integrated care through public private partnership. Adults aged between 18 and 44 (inclusive) without known diabetes and with at least one risk factor for diabetes will undergo a saliva DNA and capillary blood test and complete a questionnaire. Depending on their risk levels, participants will be stratified to high risk and low risk progressors to diabetes. The high risk progressors will undergo annual oral glucose tolerance test to detect diabetes and impaired glucose tolerance (IGT). All participants will receive a personalized report indicating their genetic and modifiable risk explained by nurses or doctors. All participants will be offered regular access to webinars for education and empowerment for 2 years. The high risk group will additionally receive a 2-year risk-stratified intervention with different combinations of care interventions. These include clinical and laboratory assessment for comprehensive evaluation of cardiovascular-kidney-metabolic risks, medical and nurse consultations, empowerment by health messages, webinars, face-to-face workshops, subsidies for medications and self-monitoring tools (e.g. CGM devices, weighing scale) to motivate behavioural change. The outcomes will be analysed within the REAIM framework (reach, effectiveness, adoption, implementation and maintenance), progresssion to prediabetes or diabetes, patient reported outcomes and cost effectiveness.

Key facts

Study ID

NCT06693934

Run by

Juliana CN Chan

People needed

9000

Starts

2024-11-23

Expected to finish

2028-05-01

Last updated by the study team

2025-03-19

Who can join

Age: 18 and older, up to 44. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Aged between 18 and 44 years old
• With at least one risk factor for diabetes

You may not qualify if…

• Known history of Diabetes
• With conditions considered not suitable by the project team (including illiteracy)
• The risk factors for diabetes include central or general obesity, family history of diabetes, smoking history, history of hypertension/ high blood glucose level/ abnormal lipid level/ vascular disease/ fatty liver, history of gestational diabetes/ polycystic ovary syndrome/ delivery of baby≥ 4kg (for women only), and less than 150mins of physical activity every week.

Where it is running

• Asia Diabetes Foundation — Hong Kong, Hong Kong (enrolling)

Full record on ClinicalTrials.gov

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