Defining Inflammatory Markers of Cardiovascular Disease in Patients With Myelodysplastic Syndromes

Recruiting now

Conditions studied: Myelodysplastic Syndromes, Adult

In brief

Why Is This Research Study Being Conducted? * The study wants to find out why people with a type of blood cancer called myelodysplastic syndromes (MDS) are more likely to have heart problems like heart disease and stroke. * Researchers also want to see if certain proteins related to inflammation in the body can help predict these heart issues in MDS patients. * By understanding this better, researchers hope to find new ways to detect and manage heart disease risks in people with MDS

Key facts

Study ID

NCT06692894

Run by

University of Vermont

People needed

30

Starts

2024-11-05

Expected to finish

2027-11-01

Last updated by the study team

2026-02-03

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥18 years
• Histologically confirmed diagnosis of MDS by bone marrow biopsy morphology, using the 2022 World Health Organization (WHO) classification for myeloid neoplasms
• Eastern Cooperative Oncology Group (ECOG) performance status ≤3
• Expected survival of at least 6 months
• Ability to provide consent

You may not qualify if…

• Cases meeting 2022 WHO criteria of MDS with excess blasts 2 as initial diagnosis
• Hematopoietic stem cell transplantation expected within 6 months

Where it is running

• University of Vermont — Burlington, Vermont, United States (enrolling)

Full record on ClinicalTrials.gov

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