A Clinical Study of MK-4318 and Diltiazem in Healthy People (MK-4318-003)

Completed · Phase 1

Conditions studied: Healthy, Pain

In brief

The goal of this study is to learn what happens to MK-4318 in a person's body over time. Researchers will compare what happens to levels of MK-4318 in people's blood when it is taken with and without diltiazem. Researchers also want to learn about the safety of MK-4318 taken with and without diltiazem and if people tolerate them.

Key facts

Study ID

NCT06692647

Run by

Merck Sharp & Dohme LLC

People needed

19

Starts

2024-02-09

Expected to finish

2024-04-11

Last updated by the study team

2024-11-18

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• The main inclusion criteria include but are not limited to the following:
• Is in good health based on medical history and physical examination
• Has a body mass index >18 and ≤32 kg/m\^2, inclusive

You may not qualify if…

• The main exclusion criteria include but are not limited to the following:
• Has a history of clinically significant endocrine, gastrointestinal, cardiovascular, hematological, hepatic, immunological, renal, respiratory, genitourinary, or major neurological (including stroke and chronic seizures) abnormalities or diseases
• Has a history of cardiac arrythmia or recurrent unexplained syncopal events

Where it is running

• Labcorb CRU, Madison (Site 0001) — Madison, Wisconsin, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.