Hypofractionated Radiotherapy for Thymic Epithelial Tumors

Recruiting now · Not applicable

Conditions studied: Thymoma and Thymic Carcinoma, Thymoma, Thymic Cancer, Thymic Epithelial Tumor

In brief

The goal of this clinical trial is to learn if hypofractionated radiotherapy works to shorten the treatment time without increasing the side effects in patients of thymic epithelial tumors. The main questions it aims to answer are: * Does Hypofractionated radiotherapy provide better results? * Can hypofractionated radiotherapy reduce toxic and side effects compared with conventional radiotherapy? Researchers will compare the efficacy and safety of hypofractionated radiotherapy after thymic tumor surgery. Participants will: * Receive hypofractionated radiotherapy or conventional radiotherapy * Visit the hospital regularly once every 12 weeks for checkups and tests

Key facts

Study ID

NCT06692062

Run by

Rongrong Zhou

People needed

100

Starts

2024-10-01

Expected to finish

2027-11-01

Last updated by the study team

2024-11-18

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients must provide written informed consent.
• 18 years old ≤ age <75 years old.
• Thymoma confirmed by pathology: type A, type AB, type B1, type B2, type B3. Thymic carcinoma. Patients with previous thymectomy were required to have complete surgical related data.
• Masaoka⁃Koga ⁃ stage Ⅰ-Ⅲ
• ECOG performance status 0-2.
• Expected survival time > 1 year.
• Participants of childbearing age must agree to use effective contraception during the trial; In women of childbearing age, a serum or urine pregnancy test must be negative.
• Patients who are not lactating.
• Sufficient bone marrow reserve and good function of important organs.

You may not qualify if…

• patients with prior thoracic radiotherapy;
• diseases not suitable for radiotherapy, such as recent myocardial infarction, active congestive heart failure;
• Uncontrolled infectious disease or other serious medical or mental illness that may interfere with care
• Patients with other malignant tumors that are not under stable control;
• Known history of mental illness, substance abuse, alcohol or drug abuse.
• Other conditions deemed unsuitable for enrollment by the attending physician.

Where it is running

• Xiangya Hospital, Central South University — Changsha, Hunan, China (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.