Absolute Bioavailability, Absorption, Metabolism, Excretion, and Mass Balance Study of [14C] NX-5948

Completed · Phase 1

Conditions studied: Healthy Volunteer

In brief

This is a Phase 1, 2-period, open-label, single-dose, fixed-sequence study to assess the absolute bioavailability, absorption, metabolism, excretion, and mass balance of \[14C\]-NX-5948. Period 1 will analyze PD (pharmacodynamics) and exploratory biomarkers. Period 2 will analyze total radioactivity and metabolite profiling.

Key facts

Study ID

NCT06691828

Run by

Nurix Therapeutics, Inc.

People needed

8

Starts

2024-11-01

Expected to finish

2024-12-05

Last updated by the study team

2025-03-12

Who can join

Age: 19 and older, up to 55. Sex: male. Healthy volunteers: accepted.

Where it is running

• Celerion — Lincoln, Nebraska, United States

Full record on ClinicalTrials.gov

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