WAter Preparation in Crohn's Disease's Imagery

Recruiting now · Not applicable

Conditions studied: Crohn Disease (CD)

In brief

The goal of this clinical trial is to compare distension quality and patient experience of water and polyethylene glycol preparation as oral contrast media in Magnetic Resonance Enterography (MRE) in patients with Crohn's disease. Thus, the main question it aims to answer is: Is water sufficient to interpret MRE from patients with Crohn's disease? Researchers will compare the standard protocol (polyethylene glycol) with water as bowel distension agent to see if it is possible to obtain a satisfying global distension of small bowel. Participants will undergo the same procedures as standard care adding questionnaires and replacing water as the bowel distension agent for the MRE for patient randomized into the experimental group.

Key facts

Study ID

NCT06690632

Run by

University Hospital, Toulouse

People needed

194

Starts

2025-01-29

Expected to finish

2028-12-01

Last updated by the study team

2026-05-08

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of Crohn's Disease,
• need for MRE (determined by patient's gastroenterologist)

You may not qualify if…

• < 18 years old,
• inability to obtain an informed consent,
• patient under guardianship or curatorship, allergy to PEG,
• contraindication to MRE (pregnancy, pace maker, claustrophobia in particular), - contraindication to phloroglucinol administration (phenylcetonuria),
• contraindication to gadolinium administration (kidney failure with glomerular filtration rate < 30/mL/1.73m², pregnancy, allergy).

Where it is running

• CHU Toulouse — Toulouse, France (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.