The Effects of Cannabidiol on the Driving Performance of Healthy Adults by Dose and Sex
Recruiting now · Phase 1 · Has a placebo group
Conditions studied: Cannabidiol Effects, Driving Performance
In brief
The objectives/purpose of this study are to comprehensively investigate the effects of non-prescription CBD on driving performance, drowsiness, sedation, and cognitive function in a large sample of healthy adults aged 18-30 years, with additional characterization of effects by dose and by sex, using a rigorous RCT design which will naturally mitigate confounding factors.
Key facts
- Study ID
- NCT06686914
- Run by
- West Virginia University
- People needed
- 300
- Starts
- 2025-06-30
- Expected to finish
- 2029-05-01
- Last updated by the study team
- 2025-10-31
Who can join
Age: 18 and older, up to 30. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Possess a current drivers' license
- Driven a motor vehicle at least once in the past 30 days
- Able to read English
- Test negative for all substances on a urine drug test and complete a test drive to ensure the absence of simulation sickness
- Not taking any daily prescription medications (excluding birth control)
- Not diagnosed with any serious chronic disease by a licensed healthcare provider (including but not limited to Alzheimer's and related dementias, Parkinson's disease or other neurodegenerative disorder, major depressive or anxiety disorder, schizophrenia or other serious mental illness, arrhythmias, cataracts, glaucoma, chronic obstructive pulmonary disease, diabetes, epilepsy, sleep apnea, and fibromyalgia)
- Have an individual willing to drive them home after testing or be taken home by study staff after testing
You may not qualify if…
- Currently smoke, vape or use tobacco products, used CBD in the past 30 days
- Used illegal drugs in the past 30 days (e.g., cocaine/crack, heroin, methamphetamine, 3,4-methylenedioxy-methamphetamine, inhalants, phencyclidine, lysergic acid diethylamide, psilocybin mushrooms, or marijuana)
- Are pregnant or lactating at time of study
Where it is running
- West Virginia University — Morgantown, West Virginia, United States (enrolling)
Full record on ClinicalTrials.gov
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