Comparison of Pulsed and Thermal Radiofrequency for Trigeminal Neuralgia
Recruiting now · Not applicable
Conditions studied: Trigeminal Neuralgia
In brief
The goal of this clinical trial is to compare the effectiveness of Pulsed Radiofrequency (PRF) with Pulsed and Thermal Radiofrequency (PRF + TRF) in treating Trigeminal Neuralgia (TN) in adults. The main questions it aims to answer are: * Does PRF or PRF + TRF provide better pain relief for patients with trigeminal neuralgia? * What is the safety profile and complication rate of PRF versus PRF + TRF? Researchers will compare the effects of PRF and PRF + TRF to see if thermal lesioning in addition to pulsed RF provides superior long-term pain relief and reduces the need for analgesic medication. Participants will: * Undergo either PRF or PRF + TRF treatment targeting the trigeminal nerve. * Be assessed for pain relief, functional status, and adverse events over a 3-month follow-up period.
Key facts
- Study ID
- NCT06684275
- Run by
- Zagazig University
- People needed
- 60
- Starts
- 2024-11-10
- Expected to finish
- 2025-04-10
- Last updated by the study team
- 2024-12-31
Who can join
Age: 18 and older, up to 60. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Adults aged 18-60 years.
- Diagnosis of classical trigeminal neuralgia, as per the International Classification of Headache Disorders criteria
- Patients experiencing unilateral, episodic facial pain for at least six months with a Numeric Rating Scale (NRS) score greater than 6, despite medical treatment.
- Able to provide informed consent.
- Agree to follow the study procedures and attend follow-up visits.
You may not qualify if…
- Patients with secondary trigeminal neuralgia (e.g., due to tumors, multiple sclerosis).
- Previous surgery or radiofrequency treatment for trigeminal neuralgia.
- Pregnant or breastfeeding women.
- Known allergies to anesthetics or other agents used in the procedure.
- Significant psychiatric disorders that may interfere with pain assessment or study participation.
- Coagulopathy or use of anticoagulants that contraindicate the procedure.
Where it is running
- Zagazig University, Faculty of Medicine — Zagazig, Sharqia Province, Egypt (enrolling)
Full record on ClinicalTrials.gov
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