Palmitic Acid and Human Microvascular Function

Starting soon · Phase 2 · Has a placebo group

Conditions studied: Microvascular Dysfunction, Microvasculature, Cardiovascular Diseases, Cardiovascular Diseases (CVD), Microvascular Health, Obesity and Overweight

In brief

The goal of this study is to learn how a supplement Quercetin can affect microvascular function. Participants will: * give two blood draws of 5 mL each * have a camera placed under the tongue to take pictures of blood vessels * have 2 laser Doppler microdialysis catheters placed on the forearm to monitor blood vessels before and after local drug infusion Researchers will compare blood vessel function of those who take estrogen supplements to those who do not.

Key facts

Study ID

NCT06683534

Run by

Medical College of Wisconsin

People needed

40

Starts

2026-07-01

Expected to finish

2030-12-01

Last updated by the study team

2026-04-29

Who can join

Age: 18 and older, up to 40. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Obesity (BMI>30)
• Aged 18-40 years
• English Speaking

You may not qualify if…

• BMI>60
• Resting SBP ≥180 mmHg or DBP ≥ 110mmHg
• Pregnancy or breastfeeding.
• Prior history of myocardial infarction
• Diagnosis of more than 1 risk factor for coronary artery disease (active smoker, diabetes mellitus- type 1 or 2, congestive heart failure, hyperlipidemia, hypertension)
• Active mouth sores that affect the buccal mucosa.

Where it is running

• Froedtert Hospital — Wauwatosa, Wisconsin, United States

Full record on ClinicalTrials.gov

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