The Impact of Local Anesthetic Solution Temperature on Epidural-related Maternal Fever
Recruiting now · Not applicable
Conditions studied: Epidural Related Maternal Fever, Analgesia, Epidural, Fever, Intrapartum Fever
In brief
This study investigates how the temperature of local anesthetics affects maternal fever related to epidural analgesia during childbirth. The research is a prospective, randomized controlled trial involving 424 participants from two hospitals. The primary objective is to investigate the impact of local anesthetic solution temperature on intrapartum fever in parturients. Secondary goals include assessing the impact on the efficacy of epidural analgesia and various maternal and neonatal outcomes. Participants will receive either 37°C or 23°C anesthetic solutions, and data will be collected on fever rates, pain scores, and other health indicators. The study runs from January 2024 to December 2026.
Key facts
- Study ID
- NCT06682416
- Run by
- The First Affiliated Hospital of Soochow University
- People needed
- 424
- Starts
- 2024-11-30
- Expected to finish
- 2027-10-01
- Last updated by the study team
- 2025-09-11
Who can join
Age: 18 and older. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- Requesting epidural analgesia;
- Aged 18 or older;
- At least 37 weeks of gestation;
- Those delivering vaginally.
You may not qualify if…
- Contraindications to epidural analgesia;
- Pre-existing fever (≥38°C) before labor;
- Use of NSAIDs or other types of antipyretics before labor;
- Multiple pregnancy (carrying more than one fetus);
- Fetal demise (stillbirth);
- Severe preeclampsia;
- Women who refuse to participate.
Where it is running
- Ethical Committee of the First Affiliated Hospital of Soochow University — Suzhou, Jiangsu, China (enrolling)
- Suzhou Municipal Hospital — Suzhou, Jiangsu, China
Full record on ClinicalTrials.gov
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