Effects of Partial Sleep Deprivation on Cardiac Output During Cycling
Recruiting now · Not applicable
Conditions studied: Sleep Deprivation
In brief
The goal of this clinical trial is to determine if attenuations in cardiac output drive the blunted blood pressure response during cycling exercise following a night of partial sleep deprivation in young healthy adults (%50 females). The secondary outcome is to assess sex differences. The main questions it aims to answer are: * Do reductions in plasma volume drive reductions in cardiac output and therefore blood pressure during exercise following a night of partial sleep deprivation? * Do sex differences exist? Participants will: * Visit the lab after a night of normal sleep and a night of partial sleep deprivation. * Keep a daily diary of their sleep and food/beverage intake. * Perform maximal and submaximal exercise on a cycle ergometer.
Key facts
- Study ID
- NCT06679543
- Run by
- University of Guelph
- People needed
- 30
- Starts
- 2025-01-02
- Expected to finish
- 2026-12-01
- Last updated by the study team
- 2026-04-28
Who can join
Age: 18 and older, up to 50. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Free of known cardiovascular or metabolic diseases or sleep disorders
- No history of smoking (within the past 3 months)
- Able to engage in physical activity assessed through the physical activity readiness questionnaire (PAR-Q+)
- No prescription of chronic medications other than oral contraceptives
- Able to abide by sleep protocols for all visits
- Individuals who are not allergic to ultrasound gel
- Individuals who are not pregnant
You may not qualify if…
- Individuals diagnosed with cardiovascular or metabolic disease or sleep disorders
- Has a history of smoking (within the past 3 months)
- Not ready to engage in physical activity as assessed by the PAR-Q+
- Individuals prescribed chronic medications other than oral contraceptives
- Unable to abide by sleep protocols for any testing visit
- Allergic to ultrasound gel
- Pregnancy
Where it is running
- University of Guelph — Guelph, Ontario, Canada (enrolling)
Full record on ClinicalTrials.gov
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