Comparison of Healing Measures Tibial Fractures Following Standard Intramedullary Nailing or Micromotion Tibial Intramedullary Nailing

Recruiting now · Not applicable

Conditions studied: Tibial Fractures

In brief

The primary purpose of this study is to perform a high-quality randomized control trial comparing intramedullary tibial nail fixation with standard design nails to a micromotion tibial nail device, to evaluate the rates of union and post-operative outcomes.

Key facts

Study ID

NCT06679049

Run by

University of Alabama at Birmingham

People needed

100

Starts

2025-04-30

Expected to finish

2027-01-31

Last updated by the study team

2026-07-14

Who can join

Age: 18 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18 - 85 years
• Stable Tibial fracture recommended for surgical intervention

You may not qualify if…

• Patients not meeting inclusion criteria
• Unstable fracture patterns e.g. those needing a secondary intervention - masquelet/cement spacer)
• Previously non-ambulatory patients
• Delayed presentation of fracture (>4 weeks)
• Fractures that the treating surgeon indicates requires additional fixation strategies to achieve stability
• Patients with an achieve infection or wound at the surgical site
• Any previous ligament or fracture surgery on the index site
• Inflammatory rheumatic disease or other rheumatic disease-
• Immune compromised patients (hepatitis, HIV, etc.)
• Unwilling or unable to participate or follow study protocol

Where it is running

• University of Alabama at Birmingham Main Hospital — Birmingham, Alabama, United States (enrolling)

Full record on ClinicalTrials.gov

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