Sleep and Light Intervention (SALI) for Menopausal Mood Dysfunction

Recruiting now · Not applicable

Conditions studied: Depression, Depression During the Menopausal Transition, Menopausal Depression

In brief

\*\*Participants must live in San Diego County\*\* The purpose of this study is to learn more about an experimental Sleep \& Light Intervention (SALI) for menopausal mood changes or depression. Researchers want to find out whether adjusting the body's internal clock-which helps regulate sleep, hormones, mood, and energy- can improve symptoms such as depression, poor sleep, and low energy during menopause.

Key facts

Study ID

NCT06678880

Run by

University of California, San Diego

People needed

120

Starts

2025-03-11

Expected to finish

2029-02-28

Last updated by the study team

2026-08-05

Who can join

Age: 45 and older, up to 75. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Women aged 45-75 years old
• Experiencing significant down, sad or hopeless feelings that are affecting their daily life
• These mood changes started or got worse during the menopause transition
• Irregular or no menstrual cycle for at least 6 months
• Non-smoking
• Located in San Diego County

You may not qualify if…

• Untreated sleep apnea
• Migraine headaches that are triggered or worsened by bright light
• Currently suicidal or psychotic
• History of bipolar disorder
• A medical condition or job where fatigue or changes in sleep schedule could be unsafe
• Planning to start, stop, or change medications in the next 4 months

Where it is running

• University of California San Diego Hillcrest Medical Center — San Diego, California, United States (enrolling)

Full record on ClinicalTrials.gov

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