Swallowing Impairments in Adults With and Without Alzheimer's Disease

Recruiting now

Conditions studied: Alzheimer Disease, Caregiver Burden, Healthy Aging, Dysphagia

In brief

This research study is investigating whether people with Alzheimer's disease (AD) experience more changes to swallowing than their healthy age-matched peers. The prevalence of swallowing impairments in moderate-severe AD is high (85-93%), yet little is known about how swallow function evolves throughout the disease course in people with AD. The overall objective of this study is to evaluate swallowing function in adults with and without Alzheimer's disease. The investigator will also be involving the primary caregivers of individuals with Alzheimer's that are enrolled in the study to better understand the impact of swallowing impairments on the primary caregivers of those with Alzheimer's Disease. Healthy adults and individuals with Alzheimer's disease will: * undergo tests of cough and swallow function * undergo tests of grip and tongue strength * complete questionnaires Caregivers of individuals with Alzheimer's disease will also complete questionnaires.

Key facts

Study ID
NCT06678100
Run by
Vanderbilt University Medical Center
People needed
240
Starts
2025-04-21
Expected to finish
2028-02-01
Last updated by the study team
2026-05-08

Who can join

Age: 60 and older. Sex: any. Healthy volunteers: accepted.

Where it is running

Full record on ClinicalTrials.gov

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