A Phase 1b Study to Assess the Safety, Tolerability, and Pharmacodynamics of AZD4144 in Participants With Established Atherosclerotic Cardiovascular and Chronic Kidney Disease.

Completed · Phase 1 · Has a placebo group

Conditions studied: Chronic Kidney Disease, Atherosclerotic Cardiovascular Disease

In brief

The purpose of this study is to evaluate the safety, tolerability and the pharmacodynamics (PD) of AZD4144 following oral administration in participants with atherosclerotic cardiovascular disease (ASCVD) and chronic kidney disease (CKD).

Key facts

Study ID
NCT06675175
Run by
AstraZeneca
People needed
29
Starts
2024-12-09
Expected to finish
2025-10-27
Last updated by the study team
2025-11-25

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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