Application of Transesophageal Echocardiography in Pre-hospital Cardiac Arrest Patients
Recruiting now · Not applicable
Conditions studied: Out-of-hospital Cardiac Arrest (OHCA)
In brief
The Use of Point-of-Care Ultrasound (POCUS), Transthoracic Echocardiography (TTE), and Transesophageal Echocardiography (TEE) in Cardiac Arrest and Acute Coronary Syndrome Patients Studies have shown that POCUS can rapidly change the management in nearly 80% of cases in emergency settings, particularly in environments such as war zones and disaster relief. TTE is highly sensitive in diagnosing acute coronary syndromes and can effectively rule out myocardial infarction. In cardiac arrest patients, TTE assists in determining cardiac activity and identifying reversible causes, such as pericardial tamponade and pneumothorax. However, TTE can be affected by suboptimal image quality due to factors like chest compression in out-of-hospital cardiac arrest (OHCA) patients. In Taiwan's emergency medical system, EMT-Ps (paramedics) undergo approximately one year of training, which enables them to provide emergency care, including ultrasound examinations, before hospital arrival. Research on pre-hospital cardiac arrest has shown that most ultrasound applications can be completed within 3 minutes and do not significantly increase on-scene time. TEE, though advantageous for its high-quality imaging and ability to reduce interruptions during chest compressions, faces challenges in pre-hospital emergency applications due to specialized training and equipment requirements. However, a study in Vienna, Austria, demonstrated that TEE could be performed and yield high-quality images in most pre-hospital cases, with an average examination time of 5.1 minutes. Several hospitals in Taiwan have begun training personnel in TEE, emphasizing the importance of establishing TEE image registries for large-scale, effective research analysis. However, these efforts also face challenges related to resources and collaboration. The research team has over three years of experience using TEE in the emergency department to examine OHCA patients, and a three-year study will be conducted to validate the efficacy of pre-hospital TEE in cardiac arrest patients.
Key facts
- Study ID
- NCT06672315
- Run by
- Jen-Tang Sun
- People needed
- 60
- Starts
- 2024-12-30
- Expected to finish
- 2027-08-31
- Last updated by the study team
- 2025-03-05
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age ≥ 18 years
- Patients with out-of-hospital cardiac arrest (OHCA)
- Non-traumatic cause of cardiac arrest
You may not qualify if…
- Presence of obvious signs of death, such as decapitation, rigor mortis, livor mortis, or decomposition.
- Family explicitly expresses a Do Not Attempt Resuscitation (DNR) order, or the patient has a documented refusal of resuscitation.
- Any condition that contraindicates the use of transesophageal echocardiography (TEE), such as esophageal tumors, preventing probe insertion.
- Patients eligible for ECPR (Extracorporeal Cardiopulmonary Resuscitation) treatment.
- Spontaneous circulation has already been stabilized before performing TEE.
Where it is running
- Far Eastern Memorinal Hospital and New Taipei City fire department — New Taipei City, Taiwan (enrolling)
Full record on ClinicalTrials.gov
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