Metabolic Effects of Fructose Intake
Completed · Not applicable
Conditions studied: Healthy
In brief
The goal of this clinical trial is to learn how fructose ingestion affects metabolic factors in healthy adults aged 18-64, with a BMI between 19 and 30 kg/m², of any sex or gender. Specifically, the study aims to examine the impact of fructose compared to glucose on circulating metabolic factors including the soluble leptin receptor. The main questions it aims to answer are: How does fructose ingestion influence levels of circulating metabolic markers, including the soluble leptin receptor? Does fructose consumption have different metabolic effects compared to glucose? Participants will: Complete a screening phone call to review their health history and eligibility. Attend two in-person visits at least two weeks apart, where they will: Fast for 8 hours beforehand. Consume a beverage containing either 75g of fructose or glucose. Have blood drawn at regular intervals for up to 5 hours after consumption to measure circulating levels of metabolic markers.
Key facts
- Study ID
- NCT06671756
- Run by
- Baylor College of Medicine
- People needed
- 8
- Starts
- 2024-12-02
- Expected to finish
- 2025-05-31
- Last updated by the study team
- 2025-07-24
Who can join
Age: 18 and older, up to 64. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Age: Participants must be between 18 and 64 years old.
- BMI: Participants must have a Body Mass Index (BMI) between 19 and 30 kg/m² (healthy weight to slightly overweight).
- Health Status: Participants must be healthy volunteers with no significant medical conditions.
- Sex/Gender: Both males and females are eligible to participate.
You may not qualify if…
- Known significant medical illness, any medications except oral contraceptives, history of fructose intolerance, pregnancy. We will not enroll BCM Medical students or individuals who work directly for any of the study investigators.
Where it is running
- Baylor St. Luke's Medical Center — Houston, Texas, United States
Full record on ClinicalTrials.gov
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