LinkSymphoKnee (LSK) Total Knee Replacement System Study - Ultra-congruent (UC)

Enrolling by invitation

Conditions studied: Osteoarthritis (OA) of the Knee, Fracture, Rheumatoid Arthritis

In brief

To collect information about implant performance and patient clinical outcomes in patients undergoing primary total knee arthroplasty with the LinkSymphoKnee total knee replacement system with ultra-congruent tibial bearing surface.

Key facts

Study ID

NCT06670651

Run by

LinkBio Corp.

People needed

600

Starts

2025-03-21

Expected to finish

2031-12-01

Last updated by the study team

2025-06-10

Who can join

Age: 18 and older, up to 79. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 18 years or older, and skeletally mature; and
• Undergoing a primary TKA for one or both knees using the cemented LinkSymphoKnee knee system as part of the surgeon's standard of care.
• Able to read and understand English (because patient-reported outcome questionnaires are not validated for all potential other languages).

You may not qualify if…

• 80 years of age or older,
• Women who are pregnant at the time of surgery,
• History of joint sepsis,
• Bone defect that requires grafting,
• Previous history of bone disease (e.g., severe osteoporosis or osteomalacia) which in the surgeon's opinion is severe enough to compromise device fixation,
• Systemic conditions affecting bone density (e.g., inflammatory arthritis or renal disease) which in the surgeon's opinion are severe enough to compromise device fixation,
• A poorly functioning contralateral total knee replacement or a contralateral revision regardless of function.

Where it is running

• OrthoAlabama Spine & Sports — Birmingham, Alabama, United States
• Illinois Bone and Joint Institute — Libertyville, Illinois, United States

Full record on ClinicalTrials.gov

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