Characterisation of the Biochemical Profile and Physiology of the Coronary Circulation in Takotsubo Syndrome

Recruiting now

Conditions studied: Tako Tsubo Cardiomyopathy

In brief

Consecutive consenting patients over the age of 18 years diagnosed with Takotsubo syndrome according to the position statement of the European Journal of Heart Failure (2016) will be included in the study. The primary endpoint is to evaluate the incidence of coronary microcirculation dysfunction and its correlation with the clinical presentation and the prognosis in patients with TAKO-Tsubo syndrome. Secondary endpoints will be to assess the incidence of in-hospital mortality, the prevalence of cardiogenic shock, the correlation between the levels of biomarkers analyzed, microvascular dysfunction, perceived quality of life, and angina severity during hospitalization and at subsequent follow-ups, and the influence of knowledge of the level of microvascular dysfunction on clinical management and prescribed therapies. Enrolment: 2 years, follow-up: 1 month and 1 year. Total: 3 years.

Key facts

Study ID

NCT06669962

Run by

A.O.U. Città della Salute e della Scienza

People needed

50

Starts

2024-07-10

Expected to finish

2027-06-27

Last updated by the study team

2024-11-01

Who can join

Age: 18 and older, up to 90. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥ 18 years;
• Diagnosis of Takotsubo syndrome
• Signing of informed consent

You may not qualify if…

• Age <18 years;
• Refusal to sign written informed consent.

Where it is running

• AOU Città della Salute e della Scienza — Turin, Turin, Italy (enrolling)

Full record on ClinicalTrials.gov

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