Correlation of Blood Serum Renalase and Microcirculation Obstruction in Patients with Acute Myocardial Infarction After Primary Percutaneous Coronary Intervention

Recruiting now

Conditions studied: Acute Myocardial Infarction

In brief

This research will explore the association between blood serum renalase and microcirculation obstruction in patients with acute myocardial infarction (AMI) after primary percutaneous coronary intervention (PCI). The investigators aim to identify potential risk factors for microcirculation obstruction in AMI patients after PPCI.

Key facts

Study ID

NCT06669520

Run by

The Third Xiangya Hospital of Central South University

People needed

200

Starts

2024-08-01

Expected to finish

2025-10-01

Last updated by the study team

2024-11-01

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥ 18 years;
• STEMI symptom onset time < 12 hours;
• STEMI symptom onset time 12-48 hours with persistent ischemic symptoms, hemodynamic instability, or life-threatening ventricular arrhythmias;
• High-risk NSTEMI;
• Emergency PCI;
• Voluntary informed consent.

You may not qualify if…

• Non-obstructive acute myocardial infarction;
• Severe chronic kidney disease (defined as estimated glomerular filtration rate < 20 mL/min per 1.73 m²);
• Life expectancy < 1 year;
• Pregnant or planning to become pregnant;
• Emergency PCI failure.

Where it is running

• The Third Xiangya Hospital of Central South University — Changsha, Hunan, China (enrolling)

Full record on ClinicalTrials.gov

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