Non-Invasive Programmed Stimulation (NIPS) to Guide the Subsequent VT Therapeutic Strategies
Recruiting now · Not applicable
Conditions studied: Ventricular Tachycardia (VT)
In brief
The aim of this study is to define the importance of non-invasive programmed stimulation (NIPS) in risk stratification of ventricular tachycardia (VT) recurrence after catheter ablation and to determine the optimal treatment strategy. The primary objective is to establish whether a new VT ablation based on NIPS inducibility will reduce the risk of VT recurrence compared to antiarrhythmic drug therapy.
Key facts
- Study ID
- NCT06669299
- Run by
- IRCCS Ospedale San Raffaele
- People needed
- 51
- Starts
- 2025-06-12
- Expected to finish
- 2027-12-01
- Last updated by the study team
- 2026-03-27
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients with an implanted ICD (all brands)
- Patients who underwent a successful (non-inducibility of any VT) Ventricular Tachycardia Ablation procedure, the "index procedure", supported by EnSite Precision or CARTO 3D mapping systems for the following etiologies: previous MI, myocarditis, ARVD, IDCM.
- Induction of monomorphic VT at NIPS 3-7days after a successful index procedure
- Age 18 years or more
- Able to provide an informed consent to participate to the study and available to respect the assessments described in the protocol.
You may not qualify if…
- Inducible VT after index procedure
- Contraindication to anticoagulants
- Presence of thrombi
- Presence of Mitral and Aortic prosthetic valve
- Recent (<3 months) myocardial infarction or unstable angina or Coronary Artery Bypass
- Pregnant or nursing
- Ventricular Tachycardia caused by reversible pathology
- < 1 Year life expectancy according to the investigator
Where it is running
- San Raffaele Hospital, Arrhythmology and Electrophysiology unit — Milan, Italy, Italy (enrolling)
Full record on ClinicalTrials.gov
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