Effect of TXA on Reducing Bruising After Filler Injection

Recruiting now · Phase 2 · Has a placebo group

Conditions studied: Facial Filler Injections, Hyaluronic Acid, Tranexamic Acid

In brief

The goal of this clinical trial is to look at the effect tranexamic acid (TXA) may have on reducing bruising, swelling, and pain after facial filler injection. The main question it aims to answer is: * Does the addition of TXA to hyaluronic acid (HA) reduce bruising, swelling, and tenderness after HA injection? Participants will receive the study medication along with the standard facial filler injection and complete surveys.

Key facts

Study ID

NCT06665594

Run by

University of Wisconsin, Madison

People needed

40

Starts

2025-12-05

Expected to finish

2026-11-01

Last updated by the study team

2026-07-23

Who can join

Age: 18 and older, up to 89. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age equal to or greater than 18 but less than or equal to 89 years.
• Participants interested in facial filler (HA) injection.
• English speaking.

You may not qualify if…

• Minors or under the age of 18
• Participant over the age of 89
• Pregnant or breast-feeding women
• Individuals unable to give consent due to another condition such as impaired decision-making capacity.
• Individuals with a history of a thrombotic event (DVT, PE, stroke, MI) or genetic disorder that increases risk of thrombosis
• Participants undergoing unilateral facial filler (HA) injection
• Participants with history of hypersensitivity to TXA or any of the other ingredients
• Participants that are on current therapeutic anticoagulation therapy and aspirin use
• Participants with stage 2 or greater renal failure
• Participants on hemodialysis or peritoneal dialysis
• History of diabetes or seizures
• Current tobacco smokers
• Acquired defective color vision

Where it is running

• University of Wisconsin - Madison — Madison, Wisconsin, United States (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.