Nutrient Profile and Muscle Protein Synthesis in Response to Corn Bread Made From Refined Versus Whole Grain Maize Flour
Running, not enrolling · Not applicable
Conditions studied: Effect of Food
In brief
The purpose of the study is to quantify and compare the serum nutrient and hormonal profile, and muscle protein synthesis rates, in response to consuming isonitrogenous amounts of a traditional East African meal, mung bean stew with a traditional African corn bread made from two different kinds of maize (whole corn flour or refined). Specific aim 1: Describe the post-prandial nutrient and hormonal profile in serum in the 3 hours following consumption of a portion of mung bean stew with traditional African corn bread made with either whole grain maize flour or refined maize flour. Specific aim 2: Compare the ability a portion of mung bean stew and traditional African corn bread made with either whole grain maize flour or refined maize flour to activate mTORC1-specific and whole muscle protein synthesis in an in vitro model of muscle.
Key facts
- Study ID
- NCT06662214
- Run by
- University of California, Davis
- People needed
- 20
- Starts
- 2025-02-24
- Expected to finish
- 2026-12-31
- Last updated by the study team
- 2026-07-06
Who can join
Age: 18 and older, up to 30. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Healthy active males and females (To be considered active, volunteers must meet the following American College of Sports Medicine's guideline for physical activity for healthy adults: performing at least 150 minutes per week of moderate-to-vigorous intensity physical activity.
- Age18-30 years
- Normal weight (BMI between 18 and 25 kg/m2
You may not qualify if…
- Health or dietary restrictions that would prevent consumption of the test foods
- Known food allergy to corn
- Anemia (low red blood cell count)
- Overweight or obesity (BMI > 25 kg/m2)
- Receiving any medication that may interfere with the study
- Metabolic or endocrine disorder that would affect the digestion, absorption, and/or physiological response to any of the nutrients ingested.
- Currently not meeting the ACSM physical activity recommendations (IPAQ score < 150 min/week of moderate-to-vigorous physical activity.
- Pregnancy
Where it is running
- UC Davis CTSC Clinical Research Center — Sacramento, California, United States
Full record on ClinicalTrials.gov
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