The Effects of Exercise Intervention on Skeletal Muscle and Other Organs in Aged Population and the Discovery of Associated Circulating Biomarkers
Recruiting now · Not applicable
Conditions studied: Age-related Functional Decline
In brief
This project aims to investigate the intricate interplay between skeletal muscle and adipose tissue during the aging process by integrating human studies. Utilizing interventional research and randomized trials combined with examining blood samples from elderly individuals engaged in exercise, we aim to investigate the effects of exercise on muscle health and explore the underlying mechanisms of muscle aging and related biomarkers. Interdisciplinary research allowed us to investigate the systemic impact of exercise on muscles. This approach allowed us to gain a better understanding of the interconnectedness of skeletal muscle and adipose tissue in the aging process and devise efficient strategies to reverse age-related changes. These findings hold promise for promoting a future society where long and healthy life is achievable for all.
Key facts
- Study ID
- NCT06660706
- Run by
- National Yang Ming Chiao Tung University
- People needed
- 100
- Starts
- 2024-04-01
- Expected to finish
- 2026-12-01
- Last updated by the study team
- 2024-10-28
Who can join
Age: 65 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- aged ≥ 65 years
- slow gait speed (<1 m/s in 6-meter walk test) or weakness (dominant handgrip strength <28 kg in men, <18 kg in women)
You may not qualify if…
- established diagnosis of dementia, Parkinsonism or other mobility-limiting, disable conditions
- active, acute diseases receiving treatment, such as cancer, heart failure, COPD and so on
- estimated life expectancy <12 months
- current nursing home residents
Where it is running
- Center for Healthy Longevity and Aging Sciences, National Yang Ming Chiao Tung University — Taipei, Taiwan (enrolling)
Full record on ClinicalTrials.gov
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