A Study to Evaluate ALN-6400 in Healthy Volunteers and Patients With Hereditary Hemorrhagic Telangiectasia (HHT)

Running, not enrolling · Phase 1/Phase 2 · Has a placebo group

Conditions studied: Hereditary Hemorrhagic Telangiectasia

In brief

The purpose of this study is to: * evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of single ascending doses of ALN-6400 in healthy volunteers * evaluate the efficacy, safety, tolerability and PD of multiple doses of ALN-6400 in adult patients with HHT

Key facts

Study ID
NCT06659640
Run by
Alnylam Pharmaceuticals
People needed
89
Starts
2024-11-07
Expected to finish
2028-06-22
Last updated by the study team
2026-07-14

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

Where it is running

Full record on ClinicalTrials.gov

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