A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors
Recruiting now · Phase 1
Conditions studied: Metastatic Solid Tumor, Advanced Solid Tumor
In brief
The main purpose of this study is to evaluate the safety and preliminary efficacy of CHS-114 in combination with toripalimab and/or other standard of care (SOC) compound(s) in participants with advanced or metastatic solid tumors.
Key facts
- Study ID
- NCT06657144
- Run by
- Coherus Oncology, Inc.
- People needed
- 154
- Starts
- 2025-04-01
- Expected to finish
- 2028-01-01
- Last updated by the study team
- 2026-07-15
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Mackay Memorial Hospital — Taipei, Taiwan (enrolling)
- City of Hope — Duarte, California, United States (enrolling)
- University of Colorado - Aurora Cancer Center — Aurora, Colorado, United States (enrolling)
- Winship Cancer Center - Emory University — Atlanta, Georgia, United States (enrolling)
- Ochsner Health — New Orleans, Louisiana, United States (enrolling)
- Henry Ford Health System — Detroit, Michigan, United States (enrolling)
- Comprehensive Cancer Center of Nevada — Las Vegas, Nevada, United States (enrolling)
- Christus St Vincent Regional Medical Center — Santa Fe, New Mexico, United States (enrolling)
- START New York — Lake Success, New York, United States (enrolling)
- David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center — New York, New York, United States (enrolling)
- Icahn School of Medicine at Mount Sinai — New York, New York, United States (enrolling)
- University of Pittsburg Medical Center _UPMC Hillman Cancer Center — Pittsburgh, Pennsylvania, United States (enrolling)
- Prisma Health Cancer Institute — Greenville, South Carolina, United States (enrolling)
- SCRI Oncology Partners — Nashville, Tennessee, United States (enrolling)
- Texas Oncology - Central South — Austin, Texas, United States (enrolling)
- START San Antonio, LLC. — San Antonio, Texas, United States (enrolling)
- Huntsman Cancer Institute, University of Utah — Salt Lake City, Utah, United States (enrolling)
- START Mountain Region, LLC. — West Valley City, Utah, United States (enrolling)
- Virginia Cancer Specialists — Fairfax, Virginia, United States (enrolling)
- National Taiwan University Hospital — Taipei, Taiwan (enrolling)
- Taipei Veterans General Hospital — Taipei, Taiwan (enrolling)
- Changhua Christian Hospital — Chang-hua, Taiwan (enrolling)
- E-Da Cancer Hospital — Kaohsiung City, Taiwan (enrolling)
- Kaohsiung Medical University Chung-Ho Memorial Hospital — Kaohsiung City, Taiwan (enrolling)
- Taichung Veterans General Hospital — Taichung, Taiwan (enrolling)
Full record on ClinicalTrials.gov
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