Impact of Different Carbohydrate Feedings on a Hydrogen Breath Curve and Self-reported Gastrointestinal Complaints

Completed · Not applicable

Conditions studied: Quality of Life

In brief

GI distress is widely prevalent among athletes, ranging from 30 to 90% in recreationally and professionally active athletes. As the recipient of nutrients, the gastrointestinal (GI) tract plays an important role in athleticism. The following pilot project aims to better understand if a fructose load after hiking under heat stress will result in a meaningful hydrogen breath elevation as a marker for malabsorption in healthy participants, and if supplementation of a multi-ingredient fermented whey supplement will result in a different hydrogen breath response rate after a heat stress hiking test.

Key facts

Study ID

NCT06648967

Run by

Arizona State University

People needed

8

Starts

2024-10-03

Expected to finish

2026-07-01

Last updated by the study team

2026-07-24

Who can join

Age: 18 and older, up to 60. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy subjects living in the United States.
• Women/Men aged between 18-60 years (50-50%).
• BMI value between ≥18.5 and ≤ 30 kg/m2.
• No physical limitations (i.e., able to perform all activities associated with daily living in an independent manner).
• Written informed consent.
• Completed PAR-Q+ without any "yes" responses.
• If currently using chronically or intermittently, willing to stop taking pre- and probiotics beginning 1 month prior to and throughout data collection.
• If currently using chronically or intermittently, willing to stop using laxatives or fiber supplements, antacids and prokinetics beginning 1 month prior to and throughout data collection.

You may not qualify if…

• Smoking.
• Clinical or self-perceived lactose intolerance.
• Clinical or self-perceived milk protein allergy.
• Diagnosed GI tract disorders or diseases.
• Musculoskeletal disorders.
• Diagnosed metabolic disorders (such as diabetes).
• Use of any medications known to affect protein metabolism (i.e., corticosteroids, non-steroidal anti-inflammatories, or prescribed acne medications).
• Chronic use of gastric acid suppressing medication or anti-coagulants.
• Chronic use of anti-inflammatory medication.
• Unwilling to stop taking pre- and probiotics beginning 1 month prior to and throughout data collection.
• Unwilling to stop using laxatives or fiber supplements, antacids and prokinetics beginning 1 month prior to and throughout data collection.

Where it is running

• Health Futures Center — Phoenix, Arizona, United States

Full record on ClinicalTrials.gov

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