Right Versus Left Thoracic Surgical Approaches for Siewert II Gastroesophageal Junction Adenocarcinoma
Recruiting now · Not applicable
Conditions studied: Siewert Type II Adenocarcinoma of Esophagogastric Junction
In brief
To explore the 5-year overall survival (OS) of right versus left thoracic surgical approaches for patients with locally advanced Siewert II gastroesophageal junction adenocarcinoma treated by neoadjuvant chemotherapy
Key facts
- Study ID
- NCT06644352
- Run by
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
- People needed
- 236
- Starts
- 2022-07-01
- Expected to finish
- 2027-07-01
- Last updated by the study team
- 2024-10-16
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Histologically confirmed gastroesophageal adenocarcinoma;
- R0 resectable Siewert Ⅱ, cT2-3N0-3M0 (AJCC V8 TNM classification);
- Have a performance status of 0 or 1 on the ECOG Performance Scale;
- Age 18-80 years old, both men and women;
- Estimated survival ≥6 months;
- Be willing and able to provide written informed consent/assent for the trial;
- Demonstrate adequate organ function ;
- Female subject of childbearing potential should have a negative urine or serum pregnancy within 7 days before enrollment. If the urine test is positive or cannot be confirmed as negative, a serum pregnancy test will be required;
- Have not received systemic or local treatment for esophageal cancer in the past.
You may not qualify if…
- Have a history of other malignant tumors in the past or at the same time;
- Previous upper abdominal surgery (excluding cholecystectomy);
- Bleeding, perforation and obstruction requiring emergency surgical treatment;
- Severe heart, lung, liver and kidney dysfunction, which the researcher thinks is not suitable for operation;
- Hydrothorax and ascites with clinical symptoms need therapeutic puncture or drainage;
- Participate in other clinical studies or less than 1 month from the end of the previous clinical study;
- Have a history of psychoactive drug abuse, alcoholism or drug abuse;
- Be unable or do not agree to bear the inspection and treatment expenses at their own expense;
- The researcher thinks that it should be excluded from this study.
Where it is running
- Cancer Hospital Chinese Academy of Medical Sciences — Beijing, China (enrolling)
Full record on ClinicalTrials.gov
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