Electroacupuncture Regulation of Immune Cells in Herpes Zoster
Recruiting now · Not applicable
Conditions studied: Herpes Zoster, Electroacupuncture, Immune
In brief
Herpes Zoster (HZ), caused by the Varicella-Zoster Virus (VZV), is a common infection characterized by localized pain and blistering, with higher incidence in females. HZ affects patients' physical health, mental well-being, and quality of life. The immune system is critical in HZ pathogenesis. Studies show acupuncture relieves pain, modulates immunity, and may lower postherpetic neuralgia (PHN) risk. However, evidence is limited on whether electroacupuncture (EA) alleviates HZ by modulating immune cells. Using mass cytometry (CyTOF), this study will analyze peripheral immune cell changes pre- and post-EA to explore its regulatory effects on HZ immunity. This study will recruit HZ patients and healthy controls (HC), dividing patients into medication-only and medication+EA groups to assess EA's potential immunomodulatory effects in HZ treatment.
Key facts
- Study ID
- NCT06643247
- Run by
- First People's Hospital of Hangzhou
- People needed
- 8
- Starts
- 2024-11-11
- Expected to finish
- 2027-12-31
- Last updated by the study team
- 2026-02-03
Who can join
Age: 50 and older, up to 70. Sex: female. Healthy volunteers: accepted.
You may not qualify if…
- Special types of herpes zoster, including ophthalmic, otic, visceral, meningeal herpes zoster, and zoster sine herpete;
- Women who are planning to conceive, pregnant, or breastfeeding;
- Patients with severe primary diseases of the circulatory, respiratory, or endocrine systems, or systemic failure;
- Patients with bleeding tendencies;
- Use of corticosteroids or immunosuppressants within the past month.
Where it is running
- The Affiliated Hangzhou First People's Hospital — Hangzhou, Zhejiang, China (enrolling)
Full record on ClinicalTrials.gov
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