Effect of Vitamin D Supplementation on Chemotherapy Side Effects After Adjuvant Chemotherapy for Breast Cancer
Recruiting now · Not applicable
Conditions studied: Vitamin D, Chemotherapy, Breast Cancer, Adverse Reaction
In brief
This randomized controlled Phase III trial was designed to evaluate the effect of vitamin D supplementation (VD) on chemotherapy side effects following adjuvant chemotherapy in breast cancer
Key facts
- Study ID
- NCT06642441
- Run by
- Jiuda Zhao
- People needed
- 100
- Starts
- 2024-12-01
- Expected to finish
- 2026-04-30
- Last updated by the study team
- 2025-01-17
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age between 18 and 80 years, with an Eastern Cooperative Oncology Group (ECOG) performance status of 0-2.
- Primary diagnosis of breast cancer confirmed by preoperative pathological examination.
- Serum 25(OH)D levels less than 20 ng/ml (50 nmol/L).
- Patients who have not previously received chemotherapy and who plan to undergo at least 4 cycles of
- Patients with adjuvant chemotherapy or combined targeted therapy.
- Life expectancy of at least 6 months.
- No other uncontrolled benign diseases at the time of recruitment.
- All patients must have complete clinical medical records.
- Willingness to voluntarily sign an informed consent form.
You may not qualify if…
- History of invasive breast cancer.
- Prior systemic treatment for the treatment or prevention of breast cancer.
- Known allergic reactions to vitamin D or calcium compounds.
- Comorbidities that may affect vitamin D or calcium balance or bone health.
- Vitamin D or calcium supplementation in the past 3 months.
- Presence of other tumors.
- Pregnant or lactating women.
- Individuals who do not wish to participate in the study.
Where it is running
- Qinghai University Affiliated Hospital — Xining, Qinghai, China (enrolling)
- Qinghai University Affiliated Hospital — Xining, Qinghai, China
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.