Effects of Inspiratory Muscle Training on Stroke Rehabilitation Outcomes

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Stroke

In brief

This study is designed to explore the effects of a 4-week protocol of inspiratory muscle training (IMT) at 50% maximum inspiratory pressure (MIP) on respiratory function, diaphragm thickness, balance control, exercise capacity, and quality of life in people after stroke. To ascertain the effect of IMT on the relationship between diaphragm muscle contraction and activation of other trunk muscles, this study also explores whether any effect of the 4-week IMT protocol on balance control is associated with changes in the anticipatory posture adjustments (APAs) time - the onset time of postural muscles during a required task (e.g., the rapid shoulder flexion test).

Key facts

Study ID

NCT06640101

Run by

Hong Kong Metropolitan University

People needed

84

Starts

2025-02-21

Expected to finish

2026-06-15

Last updated by the study team

2025-02-24

Who can join

Age: 40 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥ 40 years and < 80 years;
• breathing spontaneously;
• clinically diagnosed with ischemic and/or haemorrhagic stroke;
• duration of stroke from onset falls within 1 month to 12 months after diagnosis;
• no thoracic or abdominal surgery within the last 6 months;
• able to understand and follow verbal instructions;
• no facial palsy, or mild facial palsy without limitation of labial occlusion;
• able to maintain a resting sitting posture without feet support for at least 30 seconds;
• no cognitive impairment (Montreal Cognitive Assessment (MoCA) score ≥ 26);
• able to independently walk at least 10 meters with or without an assistive device.

You may not qualify if…

• acute myocardial infarction or acute heart failure;
• acute pain in any part of the body;
• with respiratory illness or positive clinical signs of impaired respiratory function (such as shortness of breath, hypoxemia, chronic cough and sputum retention);
• with chronic cardiovascular dysfunction;
• Trunk Impairment Scale (TIS) score ≥ 20.
• patient with a nasal feeding tube, tracheal tube and/or any condition that prevents the measurement or the implementation of the study procedure.

Where it is running

• Shenzhen Second People's Hospital — Shenzhen, None Selected, China (enrolling)

Full record on ClinicalTrials.gov

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