High - Flow Nasal Cannula Versus Conventional Nasal Cannula During Endobronchial Ultrasound Procedure
Recruiting now · Not applicable
Conditions studied: Hypoxemia During EBUS Bronchoscopy
In brief
EBUS bronchoscopy is performed in most centers under local anesthesia and moderate sedation. Both the bronchoscopy itself and the sedation can lead to decreased ventilation and a drop in oxygen saturation in the body. Typically, oxygen is administered during the procedure via a nasal cannula at a flow rate of 6l/min. The aim of the study is to compare a new method - a nasal cannula with high flow - to the standard cannula. The primary objective is to demonstrate that the new method is more effective at preventing desaturation during the procedure. Patients will be randomized into two groups before bronchoscopy and monitored. The bronchoscopy will be performed in the same way for both groups. The only difference between the groups will be in the method of oxygen administration during EBUS bronchoscopy.
Key facts
- Study ID
- NCT06637280
- Run by
- The University Clinic of Pulmonary and Allergic Diseases Golnik
- People needed
- 150
- Starts
- 2024-03-01
- Expected to finish
- 2024-11-01
- Last updated by the study team
- 2024-10-15
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Adult patients older than 18 years, ASA I - III, with normal pre-procedural pO2 (\> 8.0 kPa) and pCO2 (\< 6.7 kPa) levels without oxygen supplementation
You may not qualify if…
- - Patient refuses to participate in the study
- Contraindication for topical anesthesia, iv sedation, or bronchoscopy
- Pregnancy
- Contraindication for HFNC including nasopharyngeal obstruction and blockage
- Patient unable to tolerate HFNC 60l/min (tested before the procedure)
- Procedure shorter than 10 min
- Less than 3 EBUS-TBNAs performed
Where it is running
- University Hospital Centre Zagreb - Jordanovac — Zagreb, City of Zagreb, Croatia (enrolling)
- National and Kapodistrian University of Athens — Athens, Athens, Greece (enrolling)
- Clinica Universitaria de Pneumologia, Hospital de Santa Maria — Lisbon, Lisbon District, Portugal (enrolling)
- University Clinic Golnik — Golnik, Golnik, Slovenia (enrolling)
Full record on ClinicalTrials.gov
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