Conservative Treatment in Patients With Supraspinatus Tendon Injury.

Recruiting now · Not applicable

Conditions studied: Supraspinatus Injury, Sleep Disturbance

In brief

Rotator cuff injuries are a major cause of severe pain, often significantly impacting patients\' sleep quality. For patients waiting for surgery or those not eligible for operative treatment, conservative treatment is recommended. In cases of minor injuries, physiotherapy is as effective as surgical intervention. The aim of this study is: (1) to compare the speed, effectiveness, and durability of four implemented interventions in improving sleep quality, pain, and shoulder function, (2) to select the most optimal form of conservative treatment for patients with shoulder pain affecting sleep quality, and (3) to evaluate the expression of brain-derived neurotrophic factor (BDNF) and proBDNF (precursor) at the mRNA protein level before the planned intervention (T0), 1 month (T1), 3 months (T3), and 6 months (T6) after intervention. The study results can assist physicians and physiotherapists in providing patients with therapy that not only relieves pain and improves function but also augments sleep quality, an aspect often overlooked in the literature yet greatly impacting patients\' quality of life.

Key facts

Study ID

NCT06631976

Run by

Medical University of Lodz

People needed

40

Starts

2024-06-04

Expected to finish

2026-09-01

Last updated by the study team

2025-12-10

Who can join

Age: 40 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Symptomatic partial incomplete thickness tear of the supraspinatus tendon, with a length below 1 cm and not exceeding 50% of the tendon thickness, confirmed by ultrasound examination.
• Sleep disturbance symptoms for at least 1 month due to shoulder pain - PSQI score > 5.
• Shoulder pain disrupting the quality of sleep.
• BMI < 30.
• Age 40-75.

You may not qualify if…

• Other accompanying pain symptoms.
• History of shoulder surgery.
• Coexistence of psychiatric or neurological disorders.
• Presence of comorbidities that may disrupt sleep.
• Presence of risk factors impairing tissue regeneration and increasing the likelihood of injury progression - osteoporosis, diabetes, hypercholesterolemia.
• Alcohol dependence, nicotine addiction, passive smoking.
• Taking antibiotics from the fluoroquinolone group, sleep-affecting medications (such as melatonin, trazodone, zolpidem), antidepressants, antipsychotics, anxiolytics.
• Lack of patient consent, lack of cooperation, or impaired verbal-logical communication.

Where it is running

• Medical University of Lodz — Lodz, Łódź Voivodeship, Poland (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.