FIT Exercise in 30d of ULLS-induced Muscle Disuse

Recruiting now · Not applicable

Conditions studied: Muscle Atrophy, Muscle Weakness

In brief

This study aims to determine how flywheel-based inertial training (FIT) implemented according to principles of velocity-based training (VBT) and High-Intensity Interval Training (HIIT) affects disuse-induced physical de-conditioning including loss of voluntary muscle strength, aerobic capacity, and balance regulation.

Key facts

Study ID

NCT06631053

Run by

Lance Bollinger

People needed

16

Starts

2024-10-23

Expected to finish

2026-09-01

Last updated by the study team

2025-10-24

Who can join

Age: 35 and older, up to 45. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Regularly engaging in aerobic exercise (> 150min/wk) and resistance exercise (>1 time per week) for the past 12 months
• Education greater than or equal to bachelor's degree (any field)

You may not qualify if…

• Waist circumference < 55cm or > 90cm (F) and < 75cm or > 100cm (M)
• Body mass index < 18.5 or > 29.9
• Shoe size < 25 or >29cm.
• Not regularly engaging in exercise for previous 12 months
• Tobacco use within previous 6 months
• Blood clotting disorder
• Heart arrhythmia
• Implanted device which could negatively be affected by electrical impulse or strong magnetic field such as pacemaker, internal defibrillator, or cochlear implant
• Diagnosed cardiovascular, pulmonary, renal, or metabolic disease
• Pregnancy (within previous 6 months)
• Oral contraceptive use (within previous three months)
• High resting blood pressure (>140 systolic and/or > 90 diastolic)
• Currently or previously undergone gender-affirming therapy (hormone therapy or sexual reassignment surgery)
• Low back or leg injury in previous 6 months
• Currently taking medication to assist with sleep
• Muscle, bone, or joint injury that limits physical activity within previous 6 months
• Neurological disorder which affects balance (such as multiple sclerosis or Parkinson's disease)

Where it is running

• University of Kentucky — Lexington, Kentucky, United States (enrolling)

Full record on ClinicalTrials.gov

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