Investigate the Efficacy of Using NMN to Improve Embryo Development Capacity.
Recruiting now · Not applicable · Has a placebo group
Conditions studied: Repeated IVF Failure, Female Infertility
In brief
The objective of this study is to investigate the efficacy of NMN supplementation in enhancing embryo developmental capacity and improving IVF success rates in patients experiencing IVF failures.
Key facts
- Study ID
- NCT06629636
- Run by
- Sunkaky Medical Cooperation
- People needed
- 60
- Starts
- 2024-08-20
- Expected to finish
- 2026-12-31
- Last updated by the study team
- 2024-10-08
Who can join
Age: 32 and older, up to 42. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- Agree to participate in the study
- 32-42 years old
- Having at least one previous embryo implantation failure
- History of low Embryo quality at day3 or day5 (according to Veeck's and Gardner's Criteria)
- No major uterine or ovarian abnormalities
- BMI level 18-25kg/m2
You may not qualify if…
- Ovarian endometriosis with Chocolate cysts (AFS type 3 and 4)
- Patients who have taken different supplements such as coenzyme Q10, vitamin E, carnitine,niacin, nicotinamide, or other vitamin B3-related etc. within the previous month
- Any medical contraindication of oocyte retrieval or subsequent procedures
- Couples where the husband presents with severe sperm abnormalities
- Couples where the husband presents \<5 million/mL motile sperm
- Uterine structural anomalies
- Polycystic ovaries
- Premature ovarian failure
- Individuals who need regular medication to treat chronic diseases such as diabetes, hypertension, gout, hyperuricemia, etc.
- Individuals who need drug treatment for any mental illness such as epilepsy and depression.
- Individuals who suffer from infectious diseases such as hepatitis B, active tuberculosis, AIDS, etc.
- Cancer patients or receiving chemo/radiotherapy treatment within the past 3 years.
Where it is running
- IVF Namba Clinic, Sankaky Medical Corporation — Osaka, Osaka, Japan (enrolling)
Full record on ClinicalTrials.gov
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