Effect of Aerobic Exercise with Blood Flow Restriction on Post-exercise Hypotension in Young Adults: the Role of Histamine Receptors

Completed · Not applicable · Has a placebo group

Conditions studied: Prehypertension (elevated Blood Pressure) or Hypertension

In brief

It was hypothesized that aerobic exercise with blood flow restriction (BFR) induced post exercise hypotension (PEH), and the reduction in blood pressure (BP) was due to peripheral vasodilation via the histamine receptors. Ten male participants participated in this study. The participants were randomly assigned to walk for 10 minutes at 6.4 k/m, 0% grade with or without BFR after taking histamine receptor blockade. Following exercise, BP was measured at 10 min interval for 60 minutes. Heart rate (HR), stroke volume (SV), cardiac output (CO), mean arterial pressure (MAP), and total peripheral resistance (TPR) were evaluated.

Key facts

Study ID

NCT06629337

Run by

California Baptist University

People needed

10

Starts

2024-04-01

Expected to finish

2024-08-31

Last updated by the study team

2024-10-08

Who can join

Age: 18 and older, up to 30. Sex: male. Healthy volunteers: accepted.

You may qualify if…

• good health,
• nonsmokers
• those not taking medications that could affect cardiovascular function

You may not qualify if…

• hypertension
• muscular skeletal disorder

Where it is running

• California Baptist University — Riverside, California, United States

Full record on ClinicalTrials.gov

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