Screening Strategies Among High-risk Populations for Anal Cancer
Recruiting now · Not applicable
Conditions studied: Neoplasms, HPV-Related Anal Squamous Cell Carcinoma
In brief
The goal of the proposed research is to 1) examine the performance of emerging screening methods for anal high-grade squamous intraepithelial lesion (aHSIL), a precancerous condition of anal cancer, among populations at high risk for anal cancer and 2) characterize DNA methylation, immunologic response, and environmental factors associated with aHSIL.
Key facts
- Study ID
- NCT06628570
- Run by
- Lisa Flowers
- People needed
- 500
- Starts
- 2024-12-16
- Expected to finish
- 2027-10-01
- Last updated by the study team
- 2025-09-08
Who can join
Age: 30 and older, up to 80. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- 30-80 years of age
- Individuals with chronic impaired immune status
- History of high-grade lower genital tract neoplasia (LGTN), Zubrod Performance Status of 0-2;
You may not qualify if…
- Patients treated for aHSIL less than 6 months before screening,
- History of anal cancer and pregnant women.
Where it is running
- University of Miami Miller School of Medicine-Sylvester Cancer Center — Miami, Florida, United States (enrolling)
- University of Miami School of Medicine at Jackson Memorial Hospital (JMH) — Miami, Florida, United States (enrolling)
- Grady Memorial Hospital — Atlanta, Georgia, United States (enrolling)
- The Ponce Center — Atlanta, Georgia, United States (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.