Exercise Effects on the Neurobiology Underlying Stress-related Eating Behaviors in Veterans

Starting soon · Not applicable

Conditions studied: Overweight/Obesity, Stress

In brief

The purpose of this study is to learn more about how common lifestyle interventions, such as exercise, affect how our brains respond to performing thinking tasks and to viewing pictures of foods and various other objects. The investigators are also interested in how changes in hormones that might be different in men and women could affect how lifestyle interventions change these brain responses.

Key facts

Study ID

NCT06627569

Run by

VA Office of Research and Development

People needed

132

Starts

2026-08-01

Expected to finish

2030-08-30

Last updated by the study team

2026-07-27

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Veterans 18-75 years old
• BMI of 25 or greater
• Physically inactive
• Able to attend study visits in person in Aurora, CO

You may not qualify if…

• Currently pregnant
• History of bariatric surgery
• Current eating disorder
• Current treatment with appetite-altering medications (e.g., GLP-1 agonists)
• Contraindication to MRI (weight > 500 lbs; claustrophobia; metal or electronic devices in the body)
• Cardiovascular disease, chronic kidney disease, pulmonary disease, or diabetes
• Unable to exercise due to cardiac, pulmonary, neurologic, or orthopedic reasons

Where it is running

• Rocky Mountain Regional VA Medical Center, Aurora, CO — Aurora, Colorado, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.