Screening for Prostate Cancer Using High Resolution Micro-ultrasound Versus Multiparametric Magnetic Resonance Imaging.

Recruiting now · Phase 3

Conditions studied: Prostate Cancer Screening

In brief

The purpose of this study is to compare whether the FDA and Health Canada approved microUS is as effective as the currently used option (MRI) for imaging the prostate gland. Participants will be randomized into two groups to compare the imaging results of the current standard of care MRI and the new microUS. The study is looking to identify the most effective imaging modality to help guide whether you progress to have a prostate biopsy.

Key facts

Study ID: NCT06626022
Run by: University of Alberta
People needed: 1284
Starts: 2025-05-08
Expected to finish: 2029-11-30
Last updated by the study team: 2026-06-04

Who can join

Age: 50 and older, up to 70. Sex: male. Healthy volunteers: accepted.

You may qualify if…

Male sex;
Age 50-70;
PSA 3-20 and/or abnormal DRE;
Biopsy naïve.

You may not qualify if…

Prior personal history of prostate cancer;
Prior prostate imaging using microUS or MRI;
Contraindication to microUS or MRI;
Testosterone replacement therapy within last 12 months; or
Androgen deprivation therapy within last 12 months.

Where it is running

Urologia Clinica Bilbao — Bilbao, Spain (enrolling)
Sunnybrook Health Sciences Centre — Toronto, Ontario, Canada (enrolling)
CH de Martigues — Martigues, France (enrolling)
Vestfold Hospital Trust — Tønsberg, Norway (enrolling)
University of California, Los Angeles (UCLA) — Los Angeles, California, United States
CIUSSS du Nord-de-l'Île-de-Montréal — Montréal, Quebec, Canada
UT Southwestern Medical Center — Dallas, Texas, United States
University of Alberta — Edmonton, Alberta, Canada
University of British Columbia — Vancouver, British Columbia, Canada

Full record on ClinicalTrials.gov

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