Nantes Bariatric Surgery Cohort
Recruiting now · Not applicable
Conditions studied: Obesity
In brief
While current research suggests that inflammation of adipose tissue in obesity is linked to accelerated aging, it has yet to be determined in humans how this could enhance preventative and personalized medicine for obese individuals. The NBC study aims to investigate : 1. Whether bariatric surgery is associated with changes in biological age 2. If bariatric surgery alters adipocyte dysfunction, the microbiota and biological rhythms 3. Whether changes in adipocyte dysfunction, microbiota and biological rhythms are linked to changes in biological age. To achieve this, establishing a biocollection before, during and after bariatric surgery will be crucial in addressing these questions
Key facts
- Study ID
- NCT06625762
- Run by
- Nantes University Hospital
- People needed
- 300
- Starts
- 2026-03-23
- Expected to finish
- 2029-09-23
- Last updated by the study team
- 2026-04-03
Who can join
Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Individuals selected for bariatric surgery (starting the BC pathway within the Nantes University Hospital bariatric unit). Inclusion criteria are those of the Bariatric Surgery program.
- male or female, adult over 18 years of age
- BMI ≥ 35 kg/m2 with complication(s) or ≥ 40 kg/m2 with or without complication (the list of eligible complications is referenced in HAS 2024 recommendations). In the event of a change in access to bariatric surgery, this threshold could be revised without any substantial change to the protocol.
- having consented to their participation in the cohort
- participant affiliated to or benefiting from a social security scheme
You may not qualify if…
- Persons protected by law (guardianship or trusteeship) or deprived of their freedom,
- Pregnant women (contraindication to CB) or nursing mothers.
Where it is running
- Nantes University Hospital — Nantes, Loire-Atlantique, France (enrolling)
Full record on ClinicalTrials.gov
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